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Dovetail Genomics Micro-C, HiChIP Kits

Dovetail Genomics has launched the Dovetail Micro-C and HiChIP Kits. The Micro-C Kit is the latest offering in the company's suite of Hi-C products, offering researchers resolution of chromatin contacts down to the mono-nucleosome level. The Dovetail HiChIP combines Micro-C and ChIP-seq into one simple workflow that enables researchers to assay protein-directed alterations to chromatin architecture and its resulting impact on gene expression, the company said. Both products are made for short-read next-generation sequencing platforms.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.