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Dotmatics' Vortex for Bioinformatics

Dotmatics has launched Vortex for Bioinformatics, a new software solution that helps scientists analyze and visualize their data to make better informed decisions. According to its developers, the software can accept whole genome, antibody, protein and peptide data. Once users upload bioinformatics files into the system, Vortex displays the sequences in a variety of formats and offers access to algorithms for sequence alignment, cross-alignment, clustering, and search. The software is able to automatically select the correct analysis method based on the number and type of sequences being analyzed so that non-bioinformaticians can get results without needing to know all of the details of the underlying algorithms. Expert users on the other hand can manually select the analysis methods they would like to run and they can integrate additional methods via scripting.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.