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Dolomite Bio Injection Valve and Sample Loop

Dolomite Bio has launched a Injection Valve and Sample Loop for single cell RNA sequencing workflows. The product is a complete four-way valve module which allow barcoded mRNA capture beads in lysis buffer to efficiently flow through the RNA-Seq chip. Its design and simple microfluidic connections enable seamless switching between the injection of the bead suspension and pumping of a driving fluid. This produces minimal dead volume and bead wastage compared to traditional syringe pump methods, the company said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.