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Dolomite Bio Injection Valve and Sample Loop

Dolomite Bio has launched a Injection Valve and Sample Loop for single cell RNA sequencing workflows. The product is a complete four-way valve module which allow barcoded mRNA capture beads in lysis buffer to efficiently flow through the RNA-Seq chip. Its design and simple microfluidic connections enable seamless switching between the injection of the bead suspension and pumping of a driving fluid. This produces minimal dead volume and bead wastage compared to traditional syringe pump methods, the company said.

The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.