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DNAnexus Apollo

DNAnexus has released its DNAnexus Apollo platform for clinico-genomic data science exploration, analysis, and discovery. The platform provides a scalable cloud environment, flexible data models, as well as intuitive analysis and visualization tools for research and development teams. According to DNAnexus, pharmaceutical research and development teams can use the platform in their translational informatics research to quickly tests hypotheses and learn more about the mechanisms of action, biomarkers and targets. 

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.