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DNA Software PanelPlex

Jun 12, 2017

DNA Software has released PanelPlex, a cloud-based product designed to aid with multiplexing of molecular diagnostics for infectious disease. Customers may use the product directly through cloud computing, or may opt to have DNA Software conduct design work using the product. Features of the product include automated assay design for a particular species among a panel of its variants and its near neighbors; wet-lab-validated results; and inclusivity and exclusivity "panels" for diagnostic quality design, according to the company's website.

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Jul 15, 2019

NanoString Alzheimer’s Disease Research Panels

NanoString has developed a set of new nCounter gene expression panels for use in Alzheimer's disease research, which it created and tested in collaboration with the MODEL-AD consortium. The two panels, one for use in mouse studies and another for human studies, measure the expression of 770 genes covering 30 modules discovered in a recent study of human brain tissue. Both are available for purchase through the company's website.

Jul 12, 2019

HTG Molecular EdgeSeq Data Analytics Software Version 1.2

HTG Molecular Diagnostics has released an updated version of its HTG EdgeSeq Reveal data analytics software. According to the firm, the software allows customers to streamline sample analysis processed on the HTG EdgeSeq platform. The version 1.2 update contains improved functionality, offering data analysis from the firm's HTG EdgeSeq Precision Immuno-Oncology Panel, the HTG EdgeSeq Oncology Biomarker Panel, and the HTG EdgeSeq Mouse mRNA Tumor Response Panel.

Jul 11, 2019

Co-Diagnostics Vector Smart NAM Test

Co-Diagnostics has launched its Vector Smart NAM test, which the firm said can be used to identify the presence of West Nile virus, St. Louis encephalitis, and western equine encephalitis in mosquito populations. According to Co-Diagnostics, the assay uses multiplex PCR to help centers identify locations of the diseases. 

Jul 11, 2019

Circulomics Short Read Eliminator XS, XL

Circulomics has launched two new versions of its Short Read Eliminator kit for the depletion of short DNA fragments from high molecular weight DNA samples. The Short Read Eliminator XS kit depletes DNA up to 10 kb in size and the Short Read Eliminator XL kit DNA up to 40 kb. While Circulomics designed the kits for use with its Nanobind DNA extraction kits, researchers can also use them with other DNA extraction methods.

Jul 11, 2019

Bio-Techne RNAscope HiPlex Assay

Bio-Techne released its multiplex in situ hybridization RNAscope HiPlex Assay for tissues. It enables researchers to gain insights into cellular mechanisms and functions by combining a simplistic workflow with the capability of simultaneously detecting up to twelve RNA targets, the firm said.

The research-use-only assay is an expansion of the Advanced Cell Diagnostics RNAscope platform, an advanced in situ hybridization system that enables visualization of single-molecule gene expression with single-cell resolution directly in intact tissues.

Jul 02, 2019

ZeptoMetrix NATtrol Respiratory Verification Panel

ZeptoMetrix has released the NATtrol Respiratory Verification Panel, a 20-member respiratory panel for use by laboratories in QC applications with molecular diagnostics for infectious disease testing. ZeptoMetrix was founded in 1999 and is based in Buffalo, New York.

Jul 01, 2019

Cellecta Dual-sgRNA Libraries

Cellecta has commercially launched its dual-sgRNA libraries designed for CRISPR activation (CRISPRa) and CRISPR interference/repression (CRISPRi) genetic screens. With the modified systems, the firm said it has re-engineered the standard knockout capacity to modulate gene activitiy. The variations extend the types of genetic screenings possible. 

According to Cellecta, its dual-sgRNA CRISPRa and CRISPRi libraries improve single-sgRNA library activity because each construct expresses two different sgRNA binding distinct sites on the promoter of each gene target. The firm believes this advantage increases the likelihood that each targeted gene will be activated or repressed above a given threshold when compared to libraries that only have a single sgRNA targeting a gene promoter. 

Jun 28, 2019

23andMe MUTYH-Associated Polyposis Report

23andMe has launched a new genetic health risk report for MUTYH-Associated Polyposis (MAP), one of three main hereditary colorectal cancer syndromes. According to the firm, the report examines two genetic variants in the MUTYH gene, Y179C and G396D, associated with MAP. The firm will offer the report to new Health + Ancestry Service customers as well as existing 23andMe Health + Ancestry Service customers genotyped on its most recent platforms.

Jun 28, 2019

BillionToOne Unity Prenatal Screen

BillionToOne has commercially launched its Unity prenatal screening assay. According to BillionToOne, the assay is powered by its molecular counting technology and is the only prenatal screen that tests cell-free fetal DNA for cystic fibrosis, spinal muscular atrophy, and sickle cell disease using only one tube of the mother's blood. The firm said it will make the test available at select clinics through its early access program, with plans for a broader commercial launch later this year. 

Jun 26, 2019

AutoGen Xtract 16+

AutoGen has launched its Xtract 16+ system, which it said provides fast and high-quality DNA or RNA from molecular diagnostic, biological, clinical, and forensic sample types. According to AutoGen, the instrument can simultaneously process between 1-16 samples. The Xtract 16+ also provides full traceability of kits and samples through real-time, app-based monitoring, which automatically generates reports for LIS/LIMS. 

Jun 26, 2019

Thermo Fisher Scientific Invitrogen Collibri DNA Library Prep Kits

Thermo Fisher Scientific has launched several Invitrogen Collibri DNA Library Prep kits for use with high-throughput Illumina sequencing systems. The kits contain a tracking dye to visualize the library prep process and to show that reagents have been properly mixed. The dyes do not interfere with enzymatic reactions and do not affect the sequencing results. Four versions of the kit are available, for either physically sheared or enzymatically sheared DNA, and involving either PCR or no PCR. All kits contain adapters with unique dual indexes or combinatorial dual indexes that enable up to 24 or 96 samples to be pooled for sequencing.

Jun 26, 2019

Porvair Sciences Drosophila ChIP Kits

Porvair Sciences has launched its commercial ChIP kit range dedicated to Drosophila. The new kits deliver high-quality ChIP-ready chromatin from tissue from as little as five Drosophila specimens. According to Porvair, the new kits offer improved sensitivity. The new Chromatrap range includes Drosohila UniqSeq, ChIP-Seq, Antibodies, and Primer Sets. 

Jun 26, 2019

Expedeon Lightning-Link Metal Labeling Kits

Expedeon announced this week that it has introduced Lightning-Link Metal Labeling Kits for multiple immunoassay-based applications to support single cell analysis. According to Expedeon, the new kits will allow users to enhance the phenotypic analysis of heterogeneous cell populations, providing increased multiplexing capability compared to fluophore labeling, improved sample throughput, and research output. The firm also noted that the labeling kits only require about 30 seconds of hands-on time. 

Jun 25, 2019

GenScript Enhanced GenBrick Gene Synthesis Service

GenScript has launched an upgrade to its GenBrick Gene Synthesis platform, which gives researchers access to DNA sequences up to 200 kilobases long with 100 percent accuracy. GenScript said it has optimized the genome assembly process and enhanced its technology to better handle difficult sequences. It has also developed new technology to quickly and accurately create long DNA sequences in one step that are free of any mutations or negative clones. 

The GenBrick service has been tested and used in synthetic biology projects such as the Synthetic 2.0 Yeast Genome (Sc2.0) project, where it synthesized the long arm of yeast chromosome VI. 

Jun 24, 2019

Phitonex NovaFluor Dyes

Phitonex has launched a new suite of NovaFluor dyes, which the firm said allows researchers to rapidly increase the number of scientific questions they can answer per cell on extant flow cytometry instrumentation. According to Phitonex, the platform helps engineer optical properties to provide high resolution single cell analysis with flow cytometry. 

A man has confessed to the rape and murder of developmental biologist Suzanne Eaton, according to the New York Times.

The Irish Times reports that US lawmakers and law enforcement agencies are concerned about ties between the US and Chinese genomics firms.

Parents of children with spinal muscular atrophy tell the Washington Post they are pushing to get insurance coverage of Novartis's Zolgensma.

In PNAS this week: gene mutations in individuals with syndromic craniosynostosis, putative colorectal cancer drivers, and more.

Jul
24
Sponsored by
Hologic

This webinar will share the results of comparisons of commercially available nucleic acid amplification tests for use in routine screening of pregnant women for Group B Streptococcus (GBS).

Jul
30
Sponsored by
Mission Bio

This webinar will outline a project that performs large-scale and integrative single-cell genome and transcriptome profiling of pediatric acute lymphoblastic leukemia (ALL) cases at diagnosis, during drug treatment, and in case of relapse.

Jul
31
Sponsored by
Thermo Fisher Scientific

This webinar will provide a first-hand look at how a molecular laboratory validated and implemented a targeted next-generation sequencing-based myeloid assay to expedite the assessment of myeloid malignancies and assist in the understanding of myeloid cancers.

Sep
18
Sponsored by
Bionano Genomics

This webinar will outline how a team at Radboud University Medical Center is assessing ultra-long read optical mapping on the Bionano Saphyr system to replace classical cytogenetics approaches in routine testing and for the discovery of novel structural variants with potential scientific, prognostic, or therapeutic value that are missed by standard approaches.