Diploid's Differ | GenomeWeb

Diploid's Differ

Feb 04, 2015

Belgian bioinformatics firm Diploid has launched a beta version of Differ, a free application for OS X that lets users view, search, split, or merge VCF files easily. Interested users can download the app directly from Diploid's website, try it out, and provide feedback that will be used to improve future iterations of the app.  

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Jan 24, 2017

GenePeeks Virtual Progeny Analytics

GenePeeks launched the Virtual Progeny Analytics screening platform for reporting individual carrier status for a limited number of diseases. The technology digitally combines genetic information from two prospective parents to generate and analyze potential genetic combinations, enabling high-resolution visibility into the risk of conceiving a child with one of more than 1,000 inheritable genetic diseases, the company said. 

Jan 20, 2017

SoftGenetics ChimerMaker Software Update

SoftGenetics has launched the latest version of its ChimerMaker software, an automated chimerism analysis software. The latest version incorporate new workflow functionalities to meet the needs of leading edge HLA, molecular pathology, histocompatibility, transplant, and immunology laboratories. In addition, the software is now compatible with the company's Six Dye Chemistries, enabling labs to analyze results from more loci from human ID kits, the company said.

Jan 20, 2017

Becton Dickinson Precise WTA Kits for Single-Cell Research

Becton Dickinson has launched the BD Precise WTA kits, which provide an easier method to identify and quantify genetic information in single cells. The kits include specialized reagents that can extract RNA molecules from individual cells and then "tag" each molecule with a unique molecular signature. Researchers stain a sample with dyes and insert the treated sample into a flow cytometer where the cells are lysed, barcoded, and further prepared for sequencing. Once sequenced, the cell data is processed and analyzed by a proprietary analysis pipeline specific for RNA quantification.

Jan 20, 2017

Phase Genomics Proximo

Phase Genomics has launched Proximo, a service providing complete end-to-end genome assemblies to researchers around the globe. To create the assemblies, the company uses a modified version of the chromosome capture method, Hi-C, to measure the distances between DNA sequence. Then the company uses its proprietary software to organize DNA sequence fragment into whole chromosomes based on those measurements.

Jan 20, 2017

Dovetail Genomics Hi-C Sequencing and Assembly Service

Dovetail Genomics has launched its Dovetail Hi-C sequencing and assembly service, which yields chromosome-scale genome assemblies. The new Dovetail Hi-C service produces libraries that enables researchers to look at biological signals and chromosome rearrangements through the lens of in vivo chromatin interactions.

Jan 18, 2017

Cambridge Isotope Laboratories Mouse Express NeuCode

Cambridge Isotope Laboratories has launched Mouse Express NeuCode, a mouse feed with various combinations of labeled Lys isotopologues for MS proteomics studies. The product will increase the multiplexing potential for traditional SILAC quantitative experiments involving neuron encoding. It uses isotopologues of lysine for multiplexed relative quantification of proteins by high-resolution MS. NeuCode also drastically cuts down on labeling time compared to SILAM and allows detection of a greater number of peptides than SILAC, the company said. The product is available in one-week or three-week quantities, and each kit contains enough feed for three mice.

Jan 11, 2017

Celmatix Fertilome

Celmatix has launched Fertilome, a genetic screen that reveals how a woman's DNA may influence her reproductive health. The test analyzes a patient's blood samples for genetic factors associated with the most common reproductive conditions that can lead to fertility difficulties in women, including endometriosis, polycystic ovarian syndrome, and primary ovarian insufficiency. Fertilome is available through physicians.

Jan 11, 2017

Dolomite Bio Injection Valve and Sample Loop

Dolomite Bio has launched a Injection Valve and Sample Loop for single cell RNA sequencing workflows. The product is a complete four-way valve module which allow barcoded mRNA capture beads in lysis buffer to efficiently flow through the RNA-Seq chip. Its design and simple microfluidic connections enable seamless switching between the injection of the bead suspension and pumping of a driving fluid. This produces minimal dead volume and bead wastage compared to traditional syringe pump methods, the company said.

Jan 11, 2017

Bioline EPIK MiRNA Select Assays

Meridian Bioscience subsidiary Bioline has launched a full range of EPIK miRNA Select assays. The recent release includes all of the organisms listed on the miRBase release 21, which increases the number of EPIK miRNA assays to over 27,000. Each assay was designed in collaboration with MiRXES in silico using thermodynamics-based algorithms. They also include miRNA specific reverse transcriptase primers and hemi-nested real-time PCR primers along with Bioline reverse transcriptase, SensiSmart with SYBR Green, and optimized buffers.

Jan 09, 2017

Cynvenio ClearID Breast Cancer Test

Cynvenio Biosystems released its updated ClearID Breast Cancer blood test, which leverages a custom-developed NGS panel of 27 genes known to be altered in breast cancer. The updated test identifies circulating tumor cell burden and detects emerging genetic alterations that are associated with therapy resistance. The assay has been optimized to monitor patients with advanced breast cancer during the start of therapy and at regular intervals following treatment. 

Jan 09, 2017

Pacific Biosciences Sequel Chemistry and Software Update

Pacific Biosciences has launched a new chemistry, V2, and new software, V4, for its Sequel sequencing system that will be available on Jan. 23. The release also includes a new version of the consumable SMRT cells. The updates improve the system's ability to support applications such as structural variant detection and targeted sequencing for tasks such as metagenomics, minor variant detection, and isoform sequencing. The mean read length is now 10 to 18 kilobases, with half the data in reads larger than 20 kilobases. Throughput is now 5 to 8 gigabases, depending on sample type and sample prep method used. The system is now also capable of loading 80-kilobase sequencing libraries. The new software includes updates to the base-calling algorithm that increase accuracy and new features to the system software to support clinical research applications.

Jan 05, 2017

Core Informatics Sanger Sequencing and Microarray Genotyping Apps

Core Informatics has released two applications for its Platform for Science that are designed to help researchers execute microarray genotyping and Sanger sequencing workflows. The company's Sanger sequencing application provides data management tools for small-scale projects in both regulated and non-regulated laboratory environments. It includes capabilities for analyzing long reads as well as for validating next-generation sequencing results. The microarray genotyping application lets users track samples as well as capture and manage data as part of large-scale genotyping projects.

Jan 05, 2017

Baylor Genetics PreSeek for Prenatal Multi-Gene Sequencing Screen

Baylor Genetics has launched PreSeek, a clinical non-invasive prenatal multi-gene sequencing screen. The test requires blood and/or saliva samples from each parent, then sequences cell-free fetal DNA for de novo disease-causing variants associated with select single-gene conditions affecting the skeletal, cardiac, and neurological systems. It is complementary to traditional prenatal screening tests, the company said.

Jan 03, 2017

Fluidigm C1 Medium-Cell High-Throughput IFC

Fluidigm has released its new high-throughput integrated fluidic circuit (HT IFC) for isolating medium-sized single cells using the firm's C1 system for mRNA sequencing. The device captures up to 800 single cells, between 10 and 17 micrometers, at higher capture efficiency and comes with live, on-IFC imaging for viability and phenotypic analysis. The firm added that the new chip enables scaling of cell atlas and lineage study applications.

Dec 28, 2016

Zymo Research Sample Collection Devices

Zymo Research has launched five new sample collection devices featuring the company's DNA/RNA Shield storage reagent, which preserves the integrity and expression profiles of samples including cells, tissues, blood, plasma, serum, saliva, urine, and feces at ambient temperatures for extended periods.

The new collection devices are: DNA/RNA Shield Swab Collection Tube, ideal for mouth, nose, throat, and environmental samples; DNA/RNA Shield Blood Collection Tube, ideal for gene expression analysis, miRNA analysis, and blood-borne pathogen detection; DNA/RNA Shield Fecal Collection Tube, which can be used for miRNA analysis, pathogen detection, gene expression, and microbiomic analysis; and DNA/RNA Shield Lysis Tubes for tissues and microbes.

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Researchers were among this weekend's protesters bemoaning the new US administration, Vox reports.