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Desktop Genetics DTG-Seq Service

Desktop Genetics recently launched its DTG-Seq service, which combines targeted amplicon sequencing and internal bioinformatics expertise for validation of on- and off-target genome editing outcomes. To use DTG-Seq, customers send isolated genomic DNA samples to Desktop's sequencing provider, while Desktop handles steps such as primer design and amplicon library preparation. The company's bioinformatics team then analyzes raw FASTQ files and investigates the efficiency and distribution of CRISPR mutations at on- and/or off-target sites. Desktop then summarizes and delivers the analysis in graphical reports along with raw sequencing data files. The company said that it can detect CRISPR editing events at frequencies as low as 0.1 percent.

The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.