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DEPArray OncoSeek Panel And DEPArray LibPrep Kit

Menarini-Silicon Biosystems and Swift Biosciences have collaborated to develop and launch the DEPArray OncoSeek Panel and the DEPArray LibPrep Kit. Both products were developed to prepare and analyze tumor cells derived from formalin-fixed, paraffin-embedded tissue samples. The LibPrep kit will allow researchers to build complex NGS libraries from a few hundred FFPE cells that contain low amounts of damaged and fragmented DNA, the company said. The OncoSeek panel will allow simultaneous analysis of sequence variants and copy number alterations focused on cancer-associated genes, and employs a streamlined single tube 2-hour reaction, generating reliable ready-to-sequence Illumina-compatible libraries, the company said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.