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Definiens' Biomarker Datafication Services for Oncology

Definiens has launched a suite of biomarker datafication services for oncology clinical development programs. These services will enable pharmaceutical and biotech companies gather comprehensive data from tissue samples that they can use to make decisions about which drug candidates to advance as well as assess the potential of companion diagnostics for patient stratification. Through the service, users gain access to data such as biomarker expression profiles, biological response to therapy and continuous biomarker readouts enabling advanced decision making and data analysis.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.