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Cytox VariaTect SNP Array

Cytox has launched its VariaTect genetic biomarker test for assessing Alzheimer's disease risk. The array, developed for research use, offers a simple blood-based test that provides a comprehensive panel of AD-informative SNPs to assist in research and novel drug discovery studies. It uses a combination of whole exome association analysis, variants identified through genome wide association studies, and variants considered to be of importance in AD-associated biological pathways. This includes approximately 130,000 novel and known SNP variants in gene pathways implicated in AD aetiology. The test was developed in partnership with Thermo Fisher Scientific subsidiary Affymetrix, and will be marketed as the Axiom Dementia Research array.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.