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Cypher Genomics' Mantis

Cypher Genomics has released a new software update to automate the interpretation of sequencing data from cancer genomes. With the update, Cypher's Mantis technology will now provide rapid insight into how different genetic variants may impact cancer progression and therapeutic effectiveness, the company said. The update will also provide a summary of somatic and germline variants for single nucleotide variants and small indels, as well as resolve difficult-to-classify variants of unknown significance.

The Scan

Foxtail Millet Pangenome, Graph-Based Reference Genome

Researchers in Nature Genetics described their generation of a foxtail millet pangenome, which they say can help in crop trait improvement.

Protein Length Distribution Consistent Across Species

An analysis in Genome Biology compares the lengths of proteins across more than 2,300 species, finding similar length distributions.

Novel Genetic Loci Linked to Insulin Resistance in New Study

A team reports in Nature Genetics that it used glucose challenge test data to home in on candidate genes involved in GLUT4 expression or trafficking.

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.