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Cynvenio Concordia Cell-Free DNA Purification

Cynvenio Biosystems has launched the Concordia cell-free DNA purification sample preparation upgrade for the company's multi-template analysis liquid biopsy platform. The upgrade package enables users to purify DNA from whole blood using Thermo Fisher's Applied Biosystems MagMAX cell-free DNA isolation kit, the company said. The Concordia upgrade is now available to early access customers through the company's partnership with Thermo Fisher Scientific. Full commercial release of the upgrade kit is scheduled for the second quarter of this year.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.