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CSI Laboratories PD-L1 Expression Assay

CSI Laboratories, a private national reference laboratory specializing in cancer diagnostics, has launched a PD-L1 (programmed death-ligand 1) immunohistochemical protein expression assay, which can be used to potentially predict a patient's response to several commercially available PD-1/PD-L1 inhibitor therapies. More specifically, the assay provides a specimen's PD-L1 tumor cell reactivity score, which can be used to identify patients who are more likely to respond to certain PD-1/PD-L1 inhibitor therapies.

The Scan

Foxtail Millet Pangenome, Graph-Based Reference Genome

Researchers in Nature Genetics described their generation of a foxtail millet pangenome, which they say can help in crop trait improvement.

Protein Length Distribution Consistent Across Species

An analysis in Genome Biology compares the lengths of proteins across more than 2,300 species, finding similar length distributions.

Novel Genetic Loci Linked to Insulin Resistance in New Study

A team reports in Nature Genetics that it used glucose challenge test data to home in on candidate genes involved in GLUT4 expression or trafficking.

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.