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Covaris 96 OneTUBE-10 Adaptive Focused Acoustics Plate

Covaris has released the 96 OneTUBE-10 AFA Plate, which uses the company's Adaptive Focused Acoustics technology to eliminate mechanical DNA shearing in the next-generation sequencing library prep workflow through end repair, A-tailing, ligation, and SPRI cleanup. OneTUBE-10 is specifically designed for use with Covaris' AFA technology for DNA shearing at volumes of 10 to 50 µL; is compatible with standard heat blocks, magnets, and thermocyclers; and can be used on any liquid-handling platform, the company said.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.