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Covaris 96 OneTUBE-10 Adaptive Focused Acoustics Plate

Covaris has released the 96 OneTUBE-10 AFA Plate, which uses the company's Adaptive Focused Acoustics technology to eliminate mechanical DNA shearing in the next-generation sequencing library prep workflow through end repair, A-tailing, ligation, and SPRI cleanup. OneTUBE-10 is specifically designed for use with Covaris' AFA technology for DNA shearing at volumes of 10 to 50 µL; is compatible with standard heat blocks, magnets, and thermocyclers; and can be used on any liquid-handling platform, the company said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.