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Courtagen Spotlight Gene Panels for Neurology and Endocrinology

Courtagen Life Sciences has launched 17 new gene panels in its Spotlight line of tests, expanding its menu in neurology, endocrinology, and other disease areas. The new tests include several pain-related panels, such as migraine, neuropathic pain, and abdominal pain. They also include endocrinology-related panels for hyper/hypoglycemia (MODY+), hyperparathyroidism, and pituitary hormone deficiency, and new neurology panels for neuromuscular disorders such as periodic paralysis, dystonia, and rhabdomyolysis.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.