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Core Informatics Sanger Sequencing and Microarray Genotyping Apps

Core Informatics has released two applications for its Platform for Science that are designed to help researchers execute microarray genotyping and Sanger sequencing workflows. The company's Sanger sequencing application provides data management tools for small-scale projects in both regulated and non-regulated laboratory environments. It includes capabilities for analyzing long reads as well as for validating next-generation sequencing results. The microarray genotyping application lets users track samples as well as capture and manage data as part of large-scale genotyping projects.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.