Cole-Parmer DNA Prep Kit by Arcis Biotechnology

Feb 10, 2017

Cole-Parmer has launched the DNA Prep Kit by Arcis Biotechnology. The Arcis kit can be used for DNA and/or RNA extractions from fluids, such as blood, and requires as little as 30 µl of sample. It uses a two-step workflow that prepares samples in three minutes with high yields. The product is ideal for PCR, real-time PCR, isothermal amplification, sequencing, genetic profiling, and forensic studies, and can be easily integrated into automated processes, the company said. 

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Feb 19, 2019

Clear Labs Clear Safety NGS Platform

Clear Labs has released a software update for its Clear Safety NGS platform, which now includes Salmonella serotyping. According to the firm, food safety professional can now detect up to 40 unique Salmonella serotypes in an enriched sample in about 24 hours. With the update, Clear said that the platform allows food manufacturers and service labs to test for the presence or absence of pathogens and serotypes at the same time. In addition, the firm noted that customers can now choose if they want to test for the disease at the genus level, species level, or the serotype level. 

Feb 12, 2019

Arrow Diagnostics ArrowforNGS Microbiota Solution A/B

Arrow Diagnostics has launched two library preparation kits for bacterial 16S rRNA gene sequencing, called ArrowforNGS Microbiota Solution A/B. The kits come with dedicated analysis software. Microbiota Solution A amplifies 16S hypervariable regions V1-V2-V3 and Microbiota Solution B amplifies 16S hypervariable regions V3-V4-V6. Both kits are compatible with the Illumina MiSeq sequencing platform.

Feb 12, 2019

Varigen Biosciences Biosynthetic Gene Cluster Custom Cloning Service

Varigen Biosciences has launched custom cloning of bacterial or fungal biosynthetic gene clusters of up to 100 kb in length. The company said that its DNAtrap technology enables it to deliver intact gene cluster clones from microbes in 10 days. Varigen has cloned 32 PKS, NRPS, and other pathways of interest with high fidelity from dozens of bacterial and fungal strains. In addition, for already-cloned pathways the firm offers shuttling to its new heterologous BGC expression vector.

Feb 12, 2019

Bode Technology Forensic Genealogy Service

Bode Technology has launched a new forensic genealogy service to law enforcement investigators and crime laboratories. The service provides forensic accredited DNA services for sample handling, extraction, and confirmation testing. The tool integrates advanced DNA testing and genealogy to develop ancestral relationships between the samples and deliver leads to the firm's clients. By using its forensic laboratory, clinical testing laboratory, and experienced genealogists, Bode said it has developed a high-quality, turn-key solution for clients from sample submission through confirmation testing. 

Feb 12, 2019

Promega Maxwell RSC miRNA Plasma, Serum Kit

Promega has launched its Maxwell RSC miRNA Plasma and Serum kit. The firm said that the kit offers oncology and translational researchers a simple and automated protocol to purify circulating RNA — including miRNA — from plasma, serum, and enriched exosomes for techniques such as next-generation sequencing or droplet digital PCR. Researchers can use the kit with Promega's Maxwell RSC and RSC 48 instruments, which the firm said will reduce hands-on time for researchers and provide consistent, high-quality, and amplifiable miRNA. 

Feb 12, 2019

Myriad Genetics Prequel

Myriad Genetics commercially launched an enhanced version of the Prequel Prenatal Screen. The enhanced noninvasive prenatal screen analyzes 23 chromosome pairs instead of the standard five chromosomes (13, 18, 21, X and Y) it previously gauged. According to the company, the ability to assess additional chromosomes enhances the test's clinical utility by improving aneuploidy detection by 30 percent. Myriad is combining the NIPS Prequel tests with its Foresight Carrier Screen and is marketing them to all female patients, including women who have a high body mass index, are an ovum donor, or have a twin pregnancy. The expanded offering will be available for doctors to order on Feb. 19. 

Feb 12, 2019

Invitae NIPS

Invitae has added non-invasive prenatal screening (NIPS) to its offerings and integrated it as part of the firm's carrier screening test. The NIPS test analyzes cell-free DNA to assess whether a pregnancy is at heightened risk for three common chromosomal disorders, including trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). There is no additional charge for adding microdeletion and sex chromosome analysis. The carrier screen sequences 301 genes linked to serious genetic disorders, and now the same specimen collection kit will also enable NIPS. Invitae will begin accepting NIPS test orders next week.

Feb 08, 2019

MGI Automated Sample Prep Workstations

MGI, a subsidiary of BGI, has introduced its MGISP series of automated sample preparation workstations worldwide. The portfolio includes the MGISP-960, a workstation with options for built-in thermocycler for PCR, isotherm stage, shaker, magnetic racks, and on-deck functions that prepare up to 96 samples simultaneously. According to the firm, the tool covers several applications, including genomics, cell biology, drug discovery, and protein science. In addition, MGI has introduced the MGISP-100, a 16 sample automated workstation that it said is optimized for NGS applications. 

Feb 07, 2019

ArcticZymes T4 DNA Ligase

ArcticZymes, a Biotec Pharmacon subsidiary, has released a T4 DNA ligase, its first commercial ligase enzyme. T4 DNA ligase is the most widely used enzyme in the ligase family, and works by joining DNA fragments together. It is used in the development of kits and products for in vitro diagnostics and molecular research. The ligase is produced under strict ISO 13485 guidelines, and can be used by customers either in combination with their own enzymes or alongside other ArcticZymes enzymes.

Feb 06, 2019

Illumina NovaSeq 6000 S Prime Reagent Kits

Illumina has launched its S Prime Reagent Kits for the NovaSeq 6000 next-generation sequencing instrument. The kits, which are available in 100-, 300-, and 500-Cycle configurations, enable paired-end reads as long as 250 bases. They require run times of 13 hours for 50-base paired end reads and up to 38 hours for 250-base paired end reads. Illumina said that total throughput is between 65 and 400 gigabases, depending on the read length.

Feb 06, 2019

OncoDNA NTRK Gene Fusion Assay

OncoDNA has released its OncoNTRK assay for solid or liquid biopsies analysis of tumors with potential NTRK gene fusions. According to the firm, the assay is the first commercial kit available for NTRK 1, 2, and 3 gene fusion profiling based on RNA-sequencing. OncoDNA said that the assay is particulary interesting for use in non-small cell lung cancer, pediatric glioblastoma, and thyroid cancer.

Feb 05, 2019

Baylor Genetics Clinical Whole-Genome Sequencing for Genetic Disorders

Baylor Genetics has launched clinical whole-genome sequencing for the diagnosis of rare genetic and inherited disorders. The test covers various mutation types throughout the genome, including single-nucleotide variants, indels, copy number variants, structural variants, regions of absence of heterozygosity, and repeat expansion variants. It requires a sample from patient and parents and has a turnaround time of 8 to 10 weeks.

Feb 05, 2019

Caris Life Sciences MI Transcriptome

Caris Life Sciences has launched a whole-transcriptome assay, MI Transcriptome, to sequence the transcriptome of patients' tumors. The assay generates on average 60 million reads per patient to enable detection of fusions, splice variants, and gene expression. The company plans to submit the assay to the US Food and Drug Administration for pre-market approval review in the first half of the year.

Feb 05, 2019

Tecan NGS DreamPrep

Tecan has launched NGS DreamPrep, an automated next-generation sequencing library prep instrument. NGS DreamPrep combines Tecan's Fluent liquid handler, Infinite plate reader, and Celero DNA-Seq and Universal Plus mRNA-Seq library prep kits.

Feb 05, 2019

Saphetor VarSome Pro

Saphetor released VarSome Pro, a paid, enhanced version of the free VarSome genomic annotation software tool aimed at researchers. The Swiss company said that VarSome Pro features advanced variant filtering and annotation of whole VCF files for single and multiple samples, gene panels, exomes, and genomes. Saphetor also recently rebranded its Saphetor Portal next-generation sequencing interpretation platform as VarSome Clinical. 

NPR reports that researchers in Italy are testing a gene drive aimed at controlling mosquito populations.

Researchers may experience the effects of the government shutdown for a while, the Los Angeles Times reports.

A new study finds that the majority of patients at a Tijuana clinic received a diagnosis after first-line genome sequencing, the San Diego Union-Tribune reports.

In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.