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Cofactor Genomics Pinnacle Assay

Cofactor Genomics has launched Pinnacle, an RNA-based oncology assay which provides insights into a patient's cancer profile. The assay reports on both aberrant oncology-relevant gene expression and known cancer gene fusions detected in the tumor sample. It uses the company's software to compare each patient's cancer expression profile to Cofactor's database of thousands of expression profiles from the same cancer type, the company said. Pinnacle is currently approved for use with formalin-fixed, paraffin-embedded tumor tissue.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.