Claret Bioscience SRSLY NGS Library Prep Kit

Claret Bioscience of Santa Cruz, California has launched a directional NGS library preparation kit called SRSLY (Single Reaction Single-stranded LibrarY). SRSLY is a single-stranded approach to library preparation, and can be fine-tuned based on user preference to capture a substantial fraction of short DNA fragments. By foregoing end-polishing, the method also retains the native 5' and 3' ends of each template molecule, providing a precise snapshot of fragmentation products, the company said. The kit's main applications are to help cell-free DNA researchers analyze nucleosome positioning and to aid investigators in producing higher-quality sequencing libraries from degraded DNA sources such as FFPE samples.