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Claret Bioscience SRSLY NGS Library Prep Kit

Claret Bioscience of Santa Cruz, California has launched a directional NGS library preparation kit called SRSLY (Single Reaction Single-stranded LibrarY). SRSLY is a single-stranded approach to library preparation, and can be fine-tuned based on user preference to capture a substantial fraction of short DNA fragments. By foregoing end-polishing, the method also retains the native 5' and 3' ends of each template molecule, providing a precise snapshot of fragmentation products, the company said. The kit's main applications are to help cell-free DNA researchers analyze nucleosome positioning and to aid investigators in producing higher-quality sequencing libraries from degraded DNA sources such as FFPE samples.

The Scan

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.

Suit Over Allegations

The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director.

Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants

In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.