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Circulomics, Oxford Nanopore Technologies: Nanobind UL Library Prep Kit, Ultra-Long DNA Sequencing Kit

Circulomics and Oxford Nanopore Technologies have jointly launched two kits and a workflow to prepare ultra-high molecular weight DNA for sequencing. The method first uses the Circulomics Nanobind Big DNA Kit for DNA extraction. The DNA is then prepared for sequencing using the new Oxford Nanopore Ultra-Long DNA Sequencing Kit and the new Circulomics Nanobind UL Library Prep Kit. The workflow can result in 25 Gb of data per MinIon flow cell and 130 Gb per PromethIon flow cell with N50 read lengths of 100 kb or more.

The Scan

Genetic Ancestry of South America's Indigenous Mapuche Traced

Researchers in Current Biology analyzed genome-wide data from more than five dozen Mapuche individuals to better understand their genetic history.

Study Finds Variants Linked to Diverticular Disease, Presents Polygenic Score

A new study in Cell Genomics reports on more than 150 genetic variants associated with risk of diverticular disease.

Mild, Severe Psoriasis Marked by Different Molecular Features, Spatial Transcriptomic Analysis Finds

A spatial transcriptomics paper in Science Immunology finds differences in cell and signaling pathway activity between mild and severe psoriasis.

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.