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Circulogene BRCA1/2 Testing

Circulogene has included somatic BRCA1 and BRCA2 blood testing to its testing menu. The addition of somatic BRCA1/2 testing allows the company to perform paired somatic and germline testing, the Birmingham, Alabama-based molecular diagnostics firm said. The paired testing is a single blood-tube test that can detect acquired mutations and inherited variants in patients with advanced breast, ovarian, and other cancers.

The Scan

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.

Study Examines Relationship Between Cellular Metabolism, DNA Damage Repair

A new study in Molecular Systems Biology finds that an antioxidant enzyme shifts from mitochondria to the nucleus as part of the DNA damage response.

Stem Cell Systems Target Metastatic Melanoma in Mouse Model

Researchers in Science Translational Medicine describe a pair of stem cell systems aimed at boosting immune responses against metastatic melanoma in the brain.

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.