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Chromatrap FFPE ChIP-Seq Kit

Chromatrap has launched an updated version of its FFPE ChIP-seq kit to extract chromatin from formalin fixed paraffin embedded tissue. The new version has a shorter protocol, offers increased chromatin yield/accessible epitopes, and provides greater flexibility in chromatin sample loading for ChIP. The kit contains sufficient Protein A or Protein G based spin-columns, buffers, and reagents to perform 24 chromatin immunoprecipitation assays and up to 10 chromatin preparations. It is also compatible with both qPCR and sequencing as a downstream process.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.