Certara's D360 | GenomeWeb

Certara's D360

Feb 17, 2015

Certara has launched a new version of its D360 software. D360 provides data integration, analysis, and visualization capabilities that support early discovery through to the preclinical and clinical phases of drug development.

Version 8.0 offers access to broader and more diverse datasets, new tools for collaboration within and across organizations, and improved performance among other updates.

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Oct 20, 2016

Qiagen QIAscout for Single-Cell Isolation

Qiagen has launched QIAscout, a novel instrument for isolation of of viable single cells from samples for downstream applications. It uses the company's technology includes a high-density array with 12.000 microcrafts that can be used to isolate and recover individual cells from a cell suspension. QIAscout works with standard inverted microscopes to reliably select and release isolated single cells. The instrument is the size of a hand-held mobile device.

Oct 20, 2016

Agilent SureGuide CRISPR Libraries for Functional Genomics

Agilent Technologies has launched new CRISPR/Cas9 guide RNA (gRNA) libraries for pooled screening. 

Both genome-scale CRISPR knockout (GeCKO) and customized SureGuide gRNA libraries for functional genomics are available, manufactured on the firm's oliogonucleotide synthesis platform. 

Agilent is offering three flavors: "Ready-to-package" GeCKO plasmid libraries, "Ready-to-clone" custom libraries that can be prepared for delivery with SureVector cloning kits, and "Ready-to-amplify" custom libraries for total control over library design.

Oct 19, 2016

SeraCare Seraseq Inherited Cardiomyopathy Reference Material

SeraCare Life Sciences has launched the Seraseq Inherited Cardiomyopathy Reference Material, a multiplexed reference material for hypertrophic cardiomyopathy (HCM) testing by next-generation sequencing. It was developed in collaboration with Birgit Funke, director of clinical research and development at the Partners Healthcare Laboratory for Molecular Medicine. The Seraseq reference material combines ten common pathogenic and/or technically challenging variants for HCM in a well characterized genomic background at a 50 percent target allele frequency, the company said. This is the first testing  control product to be launched after the company's research on testing controls was published online in the Journal of Molecular Diagnostics earlier this year.

Oct 19, 2016

NanoString NCounter Vantage 3D Panels

NanoString Technologies has launched two new translational research assays, nCounter Vantage 3D DNA (SNV) Solid Tumor panel and nCounter Vantage 3D Protein Solid Tumor Signaling Pathways panel. The nCounter Vantage 3D DNA (SNV) Solid Tumor panel is designed for highly multiplexed profiling of known cancer mutations, as well as insertion and deletions from as little as five nanograms of DNA, while the nCounter Vantage 3D Solid Tumor Signaling Pathways panel enables the identification of activation state through the measurement of total proteins and phosphoproteins from a single slice of FFPE tissue or form as little as 250 ng of protein from cell or tissue lysate. The two new panels can be combined with one another as well as with the nCounter Vantage RNA panels to enable more comprehensive profiling of formalin-fixed, paraffin embedded tumor tissue.

Oct 19, 2016

Qiagen QIAseq cfDNA All-in-One Kit

Qiagen has launched the QIAseq cfDNA All-in-One kit, which combines cell-free DNA extraction and library preparation in the first dedicated solution for liquid biopsy analysis on any next-generation sequencing platform. The kit builds on the company's QIAamp technology and integrates the company's recently launched PAXgene Blood ccfDNA tube for collection and stabilization of blood samples. It creates a streamlined testing solution that allows faster, more convenient, and reliable analysis of cell-free DNA from sample collection to interpreted result, the company said.

Oct 19, 2016

Zymo Quick-cfRNA Serum and Plasma Kit

Zymo Research has launched the Quick-cfRNA Serum and Plasma kit. The kit uses the company's Zymo-Spin technology to purify cell-free RNA from up to one ml of plasma, serum, or other biological fluids. The kit produces isolated RNA immediately ready for sensitive downstream applications including RT-qPCR and next-generation sequencing. It can also be used for biomarker discovery and advanced liquid biopsy research, the company said.

Oct 19, 2016

Sygnis CovCheck Kit

Sygnis has launched the CovCheck kit, a PCR-based kit for whole genome amplification coverage to determine the quality and integrity of the amplified DNA. The kit includes 24 different sets of primer pairs each targeting a specific human chromosome and has a 96-well plate format. The product shows a strong correlation between the samples amplified and the real coverage obtained through whole genome sequencing, the company said.

Oct 19, 2016

Cambridge Epigenetix TrueMethyl Whole Genome

Cambridge Epigenetix has launched the TrueMethyl Whole Genome, an integrated workflow for processing DNA samples and epigenetic analysis. The kit incorporates the company's TrueMethyl oxidative bisulfite technology, which allows researchers to accurately quantify different DNA modifications at single-base resolution, and proprietary library preparation methods. The kit also incorporates bioinformatic tools comprised of a series of scripts for QC analysis and biological analysis of the resultant sequencing data.

Oct 19, 2016

10x Genomics Chromium Single Cell Controller

10x Genomics has launched the Chromium Single Cell Controller, a massively scalable tool for comprehensive single cell analysis. The instrument can interrogate hundred to millions of cells, and features a simple and comprehensive workflow which enables users to quickly and easily prepare single cell sequencing libraries in less than one workday, the company said. Additionally, the instrument includes an easy-to-use software suite for rapid analysis and visualization of very large single cell datasets. It can also support a variety of applications, including the existing Chromium Single Cell 3' Solution for single cell transcriptomics. The system is accompanied by Chromium Single Cell 3' reagent kits and features full compatibility with Illumina HiSeq, NextSeq and MiSeq sequencers. The Chromium Single Cell Controller is currently available with a US introductory price of $50,000.

Oct 18, 2016

Igenbio's Metagenomics Application

Igenbio has added a new module for analyzing metagenomic data to its ERGO software platform. The module lets users explore phylogenetic hierarchies, metabolic potential, as well as transcriptomic data to discover expression dynamics between samples, treatments, and conditions.

Oct 18, 2016

Genalice Map 2.4.0

Genalice has released Genalice 2.4.0, the latest iteration of of its software for secondary analysis of next-generation sequencing data. This release includes a new somatic calling module that helps users distinguish between variants found in normal and tumor tissue samples. According to the company, the new module outperforms existing tools such as MuTecT, FreeBayes, and VarScan in terms of both speed and accuracy. Other updates to the software include a tool that lets users create profiles for defined cohorts for targeted cell amplification and suppression as well as a tool for detecting copy number variants.

Oct 17, 2016

Thermo Fisher Scientific PharmacoScan

Thermo Fisher Scientific has introduced PharmacoScan, a microarray-based research tool that contains pharmacogenomic content with relevant markers involved in absorption, distribution, metabolism and excretion (ADME) pathways of commonly prescribed medicines.

Using PharmacoScan, researchers can interrogate more than 4,600 markers in nearly 1,200 genes involved in pharmacogenomics pathways with a single assay. The solution is enabled by the Axiom genotyping solution and automated GeneTitan multi-channel array plate processing instrument, and enables lot-to-lot reproducibility and data consistency and high-throughput and affordable sample processing, a key factor for multi-year pharmacogenomics profiling of prospective cohorts.

The solution was developed in collaboration with experts in the field and leading PGx consortia, such as the Clinical Pharmacogenetics Implementation Consortium, PharmaADME, and PharmGKB. Early-access customers include the University of Montreal Hospital Research Centre; University of Alberta; and leading genomic service laboratories, including RUCDR Infinite Biologics and Eurofins Genomics/AROS Applied Biotechnology, Thermo Fisher said.

Oct 14, 2016

BioBam's Blast2Go

BioBam has released version 4 of Blast2Go, its bioinformatics solution for functional analysis of transcriptomics datasets. This release offers access to proprietary and third-party algorithms for tasks such as gene prediction, functional characterization, and statistical analysis of gene sets. It also include several new resources that help developers create apps for the Blast2Go platform.

Oct 13, 2016

Good Start VeriYou CF and SMA Test

Good Start Genetics has launched its VeriYou CR and SMA test, a saliva-based screening test for two of the most common inherited genetic disorders: cystic fibrosis and spinal muscular atrophy. Patients send saliva samples to the company's CLIA-certified and CAP-accredited laboratory, where the samples are screened for 591 genetic variants. While patients can submit the kits themselves, testing must be approved by a physician. Results are delivered securely and interactively online with educational information including the ability to address follow-up questions with physicians directly and to connect with genetic counselors, the company said. 

Oct 12, 2016

Trinean DropSense96

Trinean has launched a new DropSense96 platform, a UV/VIS reader. Like the older model, the reader can still analyze 1 to 96 samples in a single experiment. The updated platform offers a significant increase of the sensitivity which allows quantification of a broader range of native samples through the company's cDrop software. The software now includes broad-use-extraction kit independent application to detect contaminants in any DNA, RNA, or protein samples. It corrects concentration determination accordingly. The cDrop software enhances the user experience and allows for better assessment of sample quality and fitness for downstream analysis, the company said.

In Nature this week: modern European bison analysis, phased diploid genome assembly algorithms, and more.

Actress Jennifer Lopez is working with NBC on a CRISPR-inspired television show, according to the Hollywood Reporter.

Researchers trace the origin of one human papillomavirus lineage to Neanderthals or Denisovans, Vox reports.

The BabySeq project faces lower-than-expected enrollment rates, according to ScienceInsider.