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Cellular Research's Precise Assays

Cellular Research has launched its Precise Assays for targeted RNA-seq experiments using single cells. Based on Cellular Research's patented molecular indexing technology, the Precise assays examine large numbers of standard or low-input mRNA samples from precious samples, or whenever absolute quantitation is required. The assays combine molecular and sample indexing in 96- and 384-sample formats, enabling customers to sequence up to 4,608 samples in one sequencing run without investment in new equipment or extensive training, Cellular Research said.

Early access customers and collaborators presented data generated with the assays at the Advances in Genome Biology and Technology conference this week in Marco Island, Fla.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.