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Cell Microsystems AIR Software Update, HexaQuad Array

Cell Microsystems has released new software for its AIR system, which automates cloning workflows using brightfield imaging to eliminate the need for fluorescent markers for sorting and confluency measurement. In addition, another new feature automates cell-sorting based on fluorescent signal intensities to characterize complex phenotypes.

Cell Microsystems has also launched the HexaQuad array, which it has designed to simultaneously run 24 distinct experiments on a single consumable. The firm said that the array is suited for labs who perform high-throughput CRISPR editing in single guide or guide pools, which allows for scaling of hundreds of clones per week and reducing a two-month workflow. Combined with the new software, the array provides a five-day workflow for researchers.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.