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CBR ReadyGen Pediatric Genetic Screening Service

CBR, a Los Angeles-based company specializing in newborn stem cell banking, has launched a new genetic service developed in collaboration with Sema4. ReadyGen is a genetic screening test that analyzes a child's DNA for more than 200 conditions that can affect children before the age of 10. These conditions are currently addressable through medication, dietary modification, newborn stem cell transplant, or other therapies, especially when detected early in a child's life, the company said. Parents can order ReadyGen online and all orders will be reviewed and approved by a physician to ensure they are medically appropriate for the child.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.