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Cartana In Situ Sequencing Reagent Kits

Cartana has launched a new range of in situ sequencing reagent kits designed to increase the efficiency and enable ISS on virtually any tissue sample. The new kits contain improved probing and sequencing technologies and come with easy-to-follow protocols for library preparation and sequencing. The HS Library Preparation Kit is used to probe directly up to 600 RNA targets in either fresh/fixed frozen or FFPE samples without the need for cDNA synthesis, and generates barcoded in situ sequencing libraries with higher efficiency compared to a previous cDNA-based library preparation approach, initially published in 2013, Cartana said. Furthermore, the new ISS kit sequences the barcodes in the libraries directly in situ, with enhanced signal-to-noise ratio and specificity compared to the previous state-of-the-art ISS technology. The new kit contains six sequencing cycles and decodes up to 600 barcodes using a standard fluorescent microscope.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.