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Canopy Biosciences Neuropathology, Immuno-Oncology Services

Canopy Biosciences has launched two new services — for immuno-oncology and neurodegenerative disease  performed on the NanoString nCounter platform. The neuropathology service consists of a multiplexed assay covering 770 established genes, providing a comprehensive assessment of neurodegenerative pathways.

The second service, the PanCancer IO 360 Gene Expression panel, enables immuno-oncology research. Using the panel, investigators can examine the expression of a set of 770 genes  including regions that contribute to the interplay between the tumor, microenvironment, and immune response in cancer. A subset of the genes in the panel also make up NanoString's 18-gene Tumor Inflammation Signature, which has been shown in studies to identify potential responders to immunotherapy drugs like PD-1 inhibitors. 

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.