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Canon BioMedical Genotyping Assay Expansion

Canon BioMedical has launched an expansion to the Novallele genotyping library with the addition of 72 new assays. The Novallele genotyping assays detect genetic variations using PCR followed by high-resolution melting analysis on any thermocycler capable of HRM. The expansion includes two novel assays, the MELAS m.3243A>G Novallele genotyping assay and LHON m.11778G>A Novallele genotyping assay, that detect mutations in mitochondrial DNA. These assays distinguish mutations that may play a role in mitochondrial disease, providing scientists a fast and simple method to detect single-nucleotide polymorphisms. The new MELAS m.3243A>G Novallele genotyping assay detects SNP of the MELAS gene, which may play a role in the MELAS disorder. Additionally, the LHON m.11778G>A Novallele genotyping assay detects a SNP of the LHON gene, which may play a role in Leber hereditary optic neuropathy. 

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.