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Cancer Genetics Focus::Renal

Cancer Genetics has launched Focus::Renal, a next-generation sequencing panel for personalized medicine in renal cancers. The panel, developed in collaboration with leading cancer centers and academic institutions, is a comprehensive and accurate genomic profiling tool covering the majority of renal cancer markers and pathways. It detects mutations in 76 renal cancer-related genes, genome-wide copy number changes, and critical single nucleotide polymorphisms, enabling clinicians to diagnose, give a prognosis, and select therapies for renal cancer patients. Focus::Renal can also be used to distinguish among the dominant three malignant and one benign renal cancer subtypes.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.