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Cancer Genetics' Focus::Lymphoma Panel

Cancer Genetics has launched Focus::Lymphoma, a CLIA-validated, next-generation sequencing panel to detect and monitor the most common mature B-cell lymphomas. The panel enables the targeted sequencing of 220 genes and has the ability to customize the reporting that provides clinically actionable information to determine patients' treatment options. The product can detect mutations in genes such as BTK and PLCG2, which have been recently attributed to therapy resistance, and offers information on genes such as MT2D, which is frequently mutated in B-cell lymphomas, but is not currently available through other commercial platforms.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.