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Cancer Genetics Complete::IO Immuno-Oncology Panel

Cancer Genetics has launched a new multiplex flow cytometry panel for use in cancer immunotherapy assessment, patient monitoring following treatment, and patient selection and stratification for clinical trials. The Complete::IO assay can help characterize the immune repertoire, immune cell populations, and the tumor microenvironment, the firm said. It detects up to 10 markers on each cell, enabling identification of rare immune cells, including central memory cells, effector cells, effector memory cells, naive CD4+ and CD8+ T cells, regulatory T and B cells, natural killer cells, and plasmacytoid dendritic cells.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.