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Bioo Scientific NEXTflex-HT Barcodes

Bioo Scientific has launched NEXTflex-HT barcodes for Illumina sequencing. Each barcode contains 12-nucleotide unique index sequences, preventing ambiguity from PCR errors or sequencing instrument errors. Each pair of consecutive barcodes is color-balanced and suitable for low-level multiplexing. The barcodes have been optimized for use with Bioo Scientific's NEXTflex-branded Rapid DNA-Seq, Cell Free DNA-Seq, mtDNA-Seq, Methyl-Seq, and DNA-Seq kits but can also be used with other Illumina library prep protocols.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.