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Bionano Genomics: Compute on Demand (COD) 1.2

Bionano Genomics has released version 1.2 of its Compute on Demand (COD) cloud compute solution. According to the company, it significantly reduces the cost and time to analyze structural variants in a human genome. Analysis results are now returned in nine hours, a 30 percent reduction in time. The improvements are enabled by the use of Microsoft Azure as a high-performance computing provider, adding to existing provider Amazon Web Services.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.