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Bioline JetSeq DNA Library Preparation Kit

Bioline, a subsidiary of Meridian Bioscience, has launched the JetSeq DNA library preparation kit. The new kit uses highly optimized enzymes and buffers, developed in collaboration with Oxford Gene Technology, to enable the preparation of the highest quality NGS sequencing-ready, adapter-ligated DNA for Illumina's Next-Generation Sequencers. The technology uses a combination of end repair and A-tailing followed by direct ligation of the adapters, thus reducing hands-on time and making the process faster and easier to use. Additionally, the technology reduces the number of required clean-up steps, significantly improving the yield and quality of sequence-ready libraries and reducing the amount of DNA required, the company said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.