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Biodesix's GeneStrat Liquid Biopsy Lung Cancer Test

Biodesix has launched GeneStrat, a PCR-based liquid biopsy test for patients with advanced non-small cell lung cancer. The assay uses BioRad's droplet digital PCR to identify clinically actionable mutations in EGFR, KRAS, and BRAF in circulating tumor DNA, which are useful in guiding targeted therapy treatment decisions in NSCLC.

This includes the EGFR T790M mutation, which is a marker of resistance to anti-EGFR drugs. According to Biodesix, turaround time for the test is 72 hours.

The Scan

WHO Seeks Booster Pause

According to CNN, the World Health Organization is calling for a moratorium on administering SARS-CoV-2 vaccine boosters until more of the world has received initial doses.

For Those Long Legs

With its genome sequence and subsequent RNAi analyses, researchers have examined the genes that give long legs to daddy longlegs, New Scientist says.

September Plans

The New York Times reports that the US Food and Drug Administration is aiming for early September for full approval of the Pfizer-BioNTech SARS-CoV-2 vaccine.

Nucleic Acids Research Papers on Targeting DNA Damage Response, TSMiner, VarSAn

In Nucleic Acids Research this week: genetic changes affecting DNA damage response inhibitor response, "time-series miner" approach, and more.