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Biocept Blood-Based Test for Prostate Cancer and Breast Cancer

Biocept has launched a CLIA-validated androgen receptor expression assay that uses a patient's blood to detect and monitor late-stage prostate cancer and a certain form of breast cancer. The assay uses circulating tumor cells from a simple blood draw to detect androgen receptor expression, which is prevalent in patients with advanced prostate cancer. The androgen receptor is also found in a subset of patients with estrogen receptor-negative, progesterone receptor-negative and Her2-negative breast cancer, known as triple negative breast cancer. 

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.