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Bio-Techne RNAscope Assays

Bio-Techne announced the launch of its RNAscope VS Duplex kit, which delivers simultaneous in situ detection of two RNA species on an automated platform. The assay enables experiments including co-localization studies and gene expression profiling in specific cell types identifiable with known markers. The assay delivers improved specificity and sensitivity with clean signals, allowing researchers to pinpoint gene expression at single-molecule sensitivity.

In addition, Bio-Techne has launched the RNAScope VS Universal HRP and AP assays, which will integrate with Roche's mRNA universal software. The assays also have protocols that allow dual staining with immunohistochemistry or immunofluorescence.

Bio-Techne has also released the updated RNAscope 2.5 VS Reagent Kit-BROWN and -RED assays, which deliver permanent and intensified staining. The firm claims the assays are suitable for archiving and are ideal when anticipating low copy target gene expression.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.