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Bio-Techne Cultrex UltiMatrix Reduced Growth Factor Basement Membrane Extract

Bio-Techne has launched the Cultrex UltiMatrix Reduced Growth Factor Basement Membrane Extract (UltiMatrix RGF BME), an extracellular matrix hydrogel for culturing organoids and pluripotent stem cells. UltiMatrix RGF BME is a dependable, high-concentration cell scaffolding matrix with compositional and physical properties specifically designed for generating advanced 2D and 3D cell culture models. It features increased total protein content, optimized extracellular matrix protein composition, high levels of entactin, and improved tensile strength while reducing the dependency on supplemental growth factors, Bio-Techne said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.