Bio Rad's Droplet Digital PCR Multiplex Mutation Screening Kits | GenomeWeb

Bio Rad's Droplet Digital PCR Multiplex Mutation Screening Kits

Apr 05, 2016

Bio-Rad has added five products to its Droplet Digital PCR (ddPCR) Multiplex Mutation Screening Kits. Each research-use only kit detects key actionable cancer mutations in certain genes — KRAS Q61, NRAS G12, NRAS G12/G13, NRAS Q61, and BRAF V600 — as well as the wild-type allele in a single reaction. The complete portfolio also includes a previously-launched KRAS G12/G13 screening kit. The kits are compatible with all of the firm's ddPCR systems. The Droplet Digital method minimizes the effects of inhibitory substances and the kits identify mutations present at allelic frequencies at or below 0.5 percent. This makes them ideal for use with formalin fixed, paraffin embedded tissue and liquid biopsy samples, the company said. 

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Jan 20, 2017

SoftGenetics ChimerMaker Software Update

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Becton Dickinson Precise WTA Kits for Single-Cell Research

Becton Dickinson has launched the BD Precise WTA kits, which provide an easier method to identify and quantify genetic information in single cells. The kits include specialized reagents that can extract RNA molecules from individual cells and then "tag" each molecule with a unique molecular signature. Researchers stain a sample with dyes and insert the treated sample into a flow cytometer where the cells are lysed, barcoded, and further prepared for sequencing. Once sequenced, the cell data is processed and analyzed by a proprietary analysis pipeline specific for RNA quantification.

Jan 20, 2017

Phase Genomics Proximo

Phase Genomics has launched Proximo, a service providing complete end-to-end genome assemblies to researchers around the globe. To create the assemblies, the company uses a modified version of the chromosome capture method, Hi-C, to measure the distances between DNA sequence. Then the company uses its proprietary software to organize DNA sequence fragment into whole chromosomes based on those measurements.

Jan 20, 2017

Dovetail Genomics Hi-C Sequencing and Assembly Service

Dovetail Genomics has launched its Dovetail Hi-C sequencing and assembly service, which yields chromosome-scale genome assemblies. The new Dovetail Hi-C service produces libraries that enables researchers to look at biological signals and chromosome rearrangements through the lens of in vivo chromatin interactions.

Jan 18, 2017

Cambridge Isotope Laboratories Mouse Express NeuCode

Cambridge Isotope Laboratories has launched Mouse Express NeuCode, a mouse feed with various combinations of labeled Lys isotopologues for MS proteomics studies. The product will increase the multiplexing potential for traditional SILAC quantitative experiments involving neuron encoding. It uses isotopologues of lysine for multiplexed relative quantification of proteins by high-resolution MS. NeuCode also drastically cuts down on labeling time compared to SILAM and allows detection of a greater number of peptides than SILAC, the company said. The product is available in one-week or three-week quantities, and each kit contains enough feed for three mice.

Jan 11, 2017

Celmatix Fertilome

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Dolomite Bio Injection Valve and Sample Loop

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Cynvenio ClearID Breast Cancer Test

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Pacific Biosciences Sequel Chemistry and Software Update

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Core Informatics Sanger Sequencing and Microarray Genotyping Apps

Core Informatics has released two applications for its Platform for Science that are designed to help researchers execute microarray genotyping and Sanger sequencing workflows. The company's Sanger sequencing application provides data management tools for small-scale projects in both regulated and non-regulated laboratory environments. It includes capabilities for analyzing long reads as well as for validating next-generation sequencing results. The microarray genotyping application lets users track samples as well as capture and manage data as part of large-scale genotyping projects.

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GenBank 217

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Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.

Mar
02
Sponsored by
VelaDx

This online seminar will highlight recent advances in the use of next-generation sequencing to detect drug-resistant mutations in patients with HIV or HCV.