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Bio-Rad QX One Droplet Digital PCR System

Bio-Rad this week launched the QX One Droplet Digital PCR system at the Association for Molecular Pathology meeting. The QX One is a single instrument that automates each step of the droplet digital PCR workflow including droplet generation, amplification, and droplet reading. The instrument has the capacity to run five 96-well plates simultaneously, providing the ability to analyze up to 480 samples per day. The system can detect four colors simultaneously for eight-plex CNV detection, five-plex mutation detection, and four-plex gene expression detection. It is compatible with current ddPCR supermixes, assays, and kits.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.