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Berkeley Lights OptoSeq 3' mRNA Library Kit

Berkeley Lights has launched its OptoSeq 3' mRNA Library kit, which allows users to directly link phenotype to genotype. The kit inculdes reagents, primers, probes, and enzymes to prepare and label individual cells for cDNA sequencing. 

According to the firm, customers can use the library prep kit to capture and link genomic information to single-cell phenotypic data in order to learn more about cellular behavior and ramp up discovery, development, and production of cell-based products. 

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.