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BD AbSeq Assay

Becton Dickinson has announced the commercial release of its BD AbSeq assay, which will analyze protein expression at the single-cell level using high-throughput sequencing. The assay integrates high-quality antibodies from the BD Pharmingen portfolio with oligonucleotides, allowing researchers to perform single-cell analysis on the firm's Rhapsody single-cell analysis system. When used in tandem, the tools allow researchers to simultaneously analyze RNA and proteins in thousands of individual cells and develop a clearer picture of the role genes and proteins play in biological systems. 

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.