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Asuragen AmplideX PCR/CE TOMM40 Kit

Asuragen has launched a kit in its AmplideX line to detect poly-T polymorphisms in the TOMM40 gene using PCR and capillary electrophoresis. The AmplideX PCR/CE TOMM40 Kit expands the firm's portfolio into the neurodegeneration, dementia progression, and Alzheimer’s disease research space. It builds on the Asuragen's success with its FMR1 and C9orf72 kits, which also reveal definitive genotypes from repetitive DNA and overcome challenges associated with high homology sequences.

The Scan

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.

Lupus Heterogeneity Highlighted With Single-Cell Transcriptomes

Using single-cell RNA sequencing, researchers in Nature Communications tracked down immune and non-immune cell differences between discoid lupus erythematosus and systemic lupus erythematosus.

Rare Disease Clues Gleaned From Mobile Element Insertions in Exome Sequences

With an approach called MELT, researchers in the European Journal of Human Genetics uncovered mobile element insertions in exomes from 3,232 individuals with or without developmental or neurological abnormalities.

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.