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Asuragen AmplideX PCR/CE TOMM40 Kit

Asuragen has launched a kit in its AmplideX line to detect poly-T polymorphisms in the TOMM40 gene using PCR and capillary electrophoresis. The AmplideX PCR/CE TOMM40 Kit expands the firm's portfolio into the neurodegeneration, dementia progression, and Alzheimer’s disease research space. It builds on the Asuragen's success with its FMR1 and C9orf72 kits, which also reveal definitive genotypes from repetitive DNA and overcome challenges associated with high homology sequences.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.