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Asuragen AmplideX PCR/CE DMPK Kit

Asuragen has launched the AmplideX PCR/CE DMPK Kit, a research-use-only assay designed to simplify analysis of repeat expansions in the DMPK gene, which is implicated in myotonic dystrophy type 1 (Steinert's disease). The repeat expansions in DMPK commonly extend beyond 1,000 CTG repeats and therefore have previously required the use of Southern blot technology to estimate their size, Asuragen noted, adding that its new kit is a significant improvement over this process.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.