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Archer Reveal ctDNA Assay

ArcherDX has launched its Archer Reveal ctDNA assay which includes full-exon coverage of the tumor suppressor TP53 as a general marker of malignancy. It was designed for high-throughput laboratories and utilizes the company's lyophilized reagents and automated bioinformatics analysis. The assay generates NGS libraries using a little as 1ng circulating, cell-free tumor DNA and requires only 5 million paired-end reads. It is also very fast and can easily generate over 24 different libraries in less than 7 hours, the company said.

The Scan

Genetic Ancestry of South America's Indigenous Mapuche Traced

Researchers in Current Biology analyzed genome-wide data from more than five dozen Mapuche individuals to better understand their genetic history.

Study Finds Variants Linked to Diverticular Disease, Presents Polygenic Score

A new study in Cell Genomics reports on more than 150 genetic variants associated with risk of diverticular disease.

Mild, Severe Psoriasis Marked by Different Molecular Features, Spatial Transcriptomic Analysis Finds

A spatial transcriptomics paper in Science Immunology finds differences in cell and signaling pathway activity between mild and severe psoriasis.

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.