Arbor Biosciences MyNGS Guides MitoDeplete Kits

Arbor Biosciences, a division of Chiral Technologies, has launched MyNGS Guides MitoDeplete Kits as part of its catalog of guide RNA pools for targeted sequencing applications. This new depletion system combines Arbor's massively parallel, high-fidelity oligo synthesis platform with Cas enzymes for efficiently targeting unwanted molecules from NGS libraries. In-stock MitoDeplete catalog kits have been designed and validated for human and mouse applications, and the company can design and synthesize kits for other custom species on demand.

MitoDeplete kits are designed for use on any NGS library containing a significant percentage of mitochondrial DNA molecules, such as ATAC-Seq libraries. CRISPR-based depletion with MitoDeplete delivers up to a 95 percent reduction in mtDNA-derived molecules in a single-step process. The human and mouse kits are available for immediate shipment in an eight-reaction kit size. Kits for custom species can be produced on request through collaboration with one of the product scientists at Arbor.