Ambry Genetics Cost-free Progeny Cloud

Jan 15, 2016

Ambry Genetics has launched Progeny Cloud, a cost-free version of Progeny Clinical, the most comprehensive genetic pedigree and clinical data management software available anywhere, built by Progeny Genetics  (a subsidiary of Ambry Genetics since April 2015). The product includes a family history questionnaire that allows patients themselves to build a more detailed and accurate record of their health history that is then integrated with genotype data and laboratory testing so clinicians can run Progeny's risk assessment algorithms. These algorithms give clinicians a clearer picture of the patients and family's health risks. Data are stored on individual secure and HIPAA-compliant servers in the Cloud. 

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Aug 22, 2017

Sunquest Mitogen LIMS and Genetic Analysis Software

Sunquest Information Systems has released Sunquest Mitogen, a new laboratory information management system and genetic analysis software platform to support molecular diagnostics and precision medicine. Mitogen, based in part on technology Sunquest acquired when it bought GeneInsight and UniConnect in 2016, is meant to help both wet and dry labs move into next-generation sequencing. 

Aug 21, 2017

Natera Signatera

Natera has launched Signatera, a research-use-only circulating tumor DNA assay. Signatera consists of analyzing whole-exome sequencing data from a patient's tumor sample to design a targeted, custom-designed assay to analyze 16 or more mutations that were identified in the tumor sample. According to Natera, the assay can detect variant allele frequencies down to 0.01 percent and is optimized to achieve high specificity by requiring detection of multiple mutations for a ctDNA-positive call, leading to fewer false positives.

Aug 11, 2017

Cynvenio Biosystems PD-L1 Expression Assay

Cynvenio Biosystems has launched its second-generation PD-L1 expression test. The blood test has improved analytic performance compared to the first-generation test, enabling highly sensitive and specific profiling and monitoring of PD-L1 expression on lung cancer cells recovered from blood. Cynvenio is offering the test from its CLIA/CAP laboratory in California with a three- to seven-day turnaround time. The test is also available to all Cynvenio customers running its LiquidBiopsy platform and workflow, the company said.

Aug 11, 2017

SeraCare Zika Virus Reference Materials

SeraCare Life Sciences has launched a set of reference materials for vlaidaing and monitoring Zika virus test methods. The AccuSet Zika Performance Panel is a 10-member panel consisting of patient samples demonstrating a range of reactivity for Zika IGM antibodies, and assessed for cross-reactivity to dengue and chikungunya. The panel is intended for use by researchers, diagnostic manufacturers, and clinical laboratories to develop, evaluate, and validate Zika serological test methods. The panel members have been comprehensively tested following the recommended US Centers for Disease Control and Prevention algorithm and using several commercially available methods.

SeraCare also launched the AccuSpan Zika RNA Linearity Panel and the AccuPlex Zika RNA Reference Material, both formulated using the company's AccuPlex recombinant virus technology. These safe, non-replicative, non-infectious, and fully extractable positive reference materials support the development and evaluation of molecular diagnostics detecting Zika virus.

Aug 10, 2017

Color Familial Hypercholesterolemia Test

Color launched a genetic test for familial hypercholesterolemia, a hereditary condition that causes high cholesterol, and if untreated, can lead to coronary heart disease. One in 50 people with high cholesterol are born with FH, and are 22 times more likely to develop coronary heart disease than those without FH and normal cholesterol. The physician-ordered test, priced at $249, analyzes three genes known to commonly cause FH: APOB, LDLR, and PCSK9. If customers want to get the FH test with Color's hereditary cancer risk test, the price is $349.

Aug 09, 2017

Exosome Diagnostics MedOncAlyzer 170

Exosome Diagnostics launched the MedOncAlyzer 170, a liquid biopsy pan-cancer panel that interrogates exosomal RNA and circulating tumor DNA in one assay. MedOncalyzer 170 is a targeted panel for tumor profiling that identifies clinically actionable and functionally important mutations across multiple cancer types, using as little as 0.5 ml of patient blood or plasma. 

Aug 09, 2017

Lexogen Small RNA-seq Library Prep Kit

Lexogen has launched a small RNA-seq library prep kit that is compatible with Illumina's sequencing instruments. Customers can work directly from total RNA or enriched small RNA from a variety of sources, including liquid biopsies, sorted cells, and tissues. In addition, inputs can range from 50 picograms to 1,000 nanograms of RNA. The workflow takes five hours with one hour of hands-on time. The kit comes with up to 96 unique barcodes. 

Aug 08, 2017

Canon BioMedical Novallele HRM Analyzer

Canon BioMedical has launched the Novallele HRM Analyzer, web-based software capable of analyzing data from different thermocyclers and well plate formats. The software provides an intuitive and easy-to-use graphical interface with comprehensive algorithms capable of analyzing high-resolution melting (HRM) data from different thermocyclers, Canon said. The software also complements Canon's Novallele genotyping assays, in conjunction with the Novallele Controls Sets, to analyze HRM data.

Aug 07, 2017

Geneformics D Distributed Cloud Compression Technology

Geneformics Data Systems today introduced Geneformics D, a distributed cloud compression system that promises to boost the speed of genomics data uploads, downloads, storage, and archiving by tenfold and reduce costs by 90 percent. Geneformics D is currently integrated into Amazon Web Services infrastructure, and Geneformics said it is working on versions for other cloud platforms. 

Aug 03, 2017

DNAStack Genomics Software Update

DNAStack has released an update to its genomics software platform. The cloud-based system features a new application called Workflows to assist researchers and clinicians in building, running, and sharinge bioinformatics workflows across sites. The software remains free for research; DNAStack charges per use for computation and data storage.

Aug 03, 2017

Swift Biosciences Accel-NGS 2S Indexed Adaptors

Swift Biosciences has launched Accel-NGS 2S Indexed Adaptors, a set of 96 single indices that work in combination with Illumina TruSeq adaptors to provide up to 768 unique dual-index combinations. The kit will enable users to prepare up to 96 single-indexed samples and up to 768 dual-indexed samples per run. According to the company, the kit should help prevent misassignment and index hopping as well as enable detection of low-frequency variants.

Aug 02, 2017

Bioline JetSeq Clean Kit

Bioline, a subsidiary of Meridian Bioscience, has launched the JetSeq Clean Kit, a clean-up system for next-generation sequencing workflows. The kit uses paramagnetic bead technology to purify nucleic acid fragments during NGS library prep. It removes salts, primers, primer-dimers, and dNTPs while selectively binding library fragments to magnetic particles based on their size.

Aug 02, 2017

ArcherDx VariantPlex Core Myeloid Panel

ArcherDx has launched the Archer VariantPlex Core Myeloid panel, a next-generation sequencing-based targeted panel that analyzes 37 genes related to myeloid malignancies. The company said the panel uses molecular barcoded reads, and can detect FLT3 internal tandem duplications, variants that are present in more than 20 percent of acute myeloid leukemia cases and are challenging to detect in NGS data. VariantPlex assays are provided in eight-strip, single-use lyophilized library preparation reagents that require no master mixes.

ArcherDx said that it also plans to launch a VariantPlex Myeloid panel, which expands the number of genes to 72.

Aug 02, 2017

Asuragen Expanded QuantideX qPCR BCR-ABL Portfolio

Asuragen has launched a new CE-marked QuantideX qPCR BCR-ABL minor kit for identifying minor (e1a2) BCR-ABL fusion transcripts in patients with chronic myeloid leukemia. The new test joins the firm's existing FDA-cleared and CE-marked QuantideX qPCR BCR-ABL IS Kit that covers major (e13a2, e14a2) fusions.

The two kits can be combined in a streamlined and common workflow, and Asuragen said it is also expanding the capabilities of its QuantideX Reporter, analysis software, which accompanies the CE-marked QuantideX qPCR BCR-ABL IS Kit, to allow laboratories the ability to report CML patient disease burden on the International Scale after reviewing ABL1 copy number, in compliance with European LeukemiaNet guidelines.

Aug 02, 2017

Integrated DNA Technologies Alt-R S.p. HiFi Cas9 Nuclease 3NLS Enzyme

Integrated DNA Technologies has launched the Alt-R S.p. HiFi Cas9 Nuclease 3NLS enzyme, a Cas9 enzyme variant that extensively reduces off-target effects in CRISPR genome editing without compromising on-target activity. This enzyme is a recombinant S. pyogenes Cas9 mutant that improves specificity while maintaining a high editing efficiency similar to wild-type Cas9, the company said. 

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