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Almac Diagnostics Services ClaraT Total mRNA Report

Almac Diagnostic Services of Craigavon, Northern Ireland, is launching the complete version of its ClaraT Total mRNA Report at the European Society for Medical Oncology meeting in Barcelona this weekend. The report content has expanded from an initial version launched a year ago, Almac said, and now includes 92 gene expression signatures, 100 single-gene drug targets, and more than 7,000 additional biology-linked genes categorized by 10 hallmarks of cancer. The research-use-only product uses RNA sequencing alongside proprietary bioinformatics to provide investigators with an interactive report that facilitates visualization of novel molecular subgroups within a sample cohort and key discriminating biology in individual tumor samples, the company said.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.