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Agilent Technologies 4200 TapeStation System

Agilent Technologies has launched the 4200 TapeStation system, a fully automated instrument that enables scientists to rapidly analyze up to 96 DNA samples at a time. The system enables end-to-end quality control of samples and libraries in any sequencing workflow, using any number of samples from one to 96, at a constant cost per sample, Agilent said in a statement. The system employs a range of prepackaged kits for RNA, DNA, and genomic DNA samples, including two new kits, the D5000 and HS D5000 ScreenTape assays, which have been specifically designed for analyzing DNA fragments and smears of up to 5,000 base pairs.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.